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Results for "

NSC 718781-d6

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Acyltransferase (1) ADC Cytotoxin (2) ADC Linker (1) Adenosine Kinase (1) Adrenergic Receptor (3) Akt (10) Amino Acid Derivatives (10) Aminopeptidase (1) AMPK (3) Androgen Receptor (1) Antibiotic (23) Antifolate (3) Apoptosis (92) Arp2/3 Complex (1) Aryl Hydrocarbon Receptor (1) Atg4 (1) Autophagy (47) Bacterial (32) Bcl-2 Family (3) Bcr-Abl (2) Biochemical Assay Reagents (5) c-Myc (1) Calcium Channel (7) Carbonic Anhydrase (1) Casein Kinase (1) CCR (1) CDK (5) Checkpoint Kinase (Chk) (2) Chloride Channel (3) COX (13) Cuproptosis (1) Cytochrome P450 (4) Deubiquitinase (2) Dihydroorotate Dehydrogenase (1) Dipeptidyl Peptidase (1) DNA Alkylator/Crosslinker (14) DNA Methyltransferase (5) DNA Stain (2) DNA/RNA Synthesis (34) Dopamine Receptor (3) Drug Metabolite (4) E1/E2/E3 Enzyme (5) EGFR (14) Endogenous Metabolite (70) Epigenetic Reader Domain (2) ERK (2) Ferroptosis (9) FGFR (2) Filovirus (2) Flavivirus (2) Fluorescent Dye (2) Free Fatty Acid Receptor (1) Fungal (9) Gli (2) GLUT (2) GSK-3 (3) HBV (1) HCV (7) HDAC (3) HIF/HIF Prolyl-Hydroxylase (6) Histamine Receptor (4) Histone Acetyltransferase (4) Histone Demethylase (2) Histone Methyltransferase (6) HIV (14) HSP (4) HSV (2) IAP (1) Influenza Virus (9) Interleukin Related (2) IRE1 (1) Isotope-Labeled Compounds (81) JAK (4) JNK (1) Keap1-Nrf2 (4) Kinesin (1) LPL Receptor (1) MDM-2/p53 (10) Microtubule/Tubulin (12) Mitochondrial Metabolism (2) Mitophagy (5) MMP (2) Molecular Glues (1) mTOR (3) nAChR (2) Necroptosis (1) NF-κB (9) NO Synthase (1) Notch (3) Nucleoside Antimetabolite/Analog (16) Orthopoxvirus (17) P-glycoprotein (2) p38 MAPK (1) Parasite (23) PARP (2) PD-1/PD-L1 (1) PERK (1) Phosphatase (8) Phosphodiesterase (PDE) (3) PI3K (1) PKC (10) Potassium Channel (5) PPAR (2) PROTACs (1) Proteasome (3) RABV (1) RAR/RXR (2) Ras (4) Reactive Oxygen Species (9) RET (1) Reverse Transcriptase (3) SARS-CoV (3) Ser/Thr Protease (2) Serotonin Transporter (6) SGLT (2) SHP2 (2) Sodium Channel (4) Src (1) STAT (6) Stearoyl-CoA Desaturase (SCD) (1) Syk (1) TET Protein (2) Topoisomerase (21) TRP Channel (1) VDAC (1) VEGFR (1) Virus Protease (2) Wnt (4) YAP (1) β-catenin (1)
By Research Areas:	Cancer (316) Cardiovascular Disease (15) Endocrinology (7) Infection (84) Inflammation/Immunology (50) Metabolic Disease (29) Neurological Disease (34)
Click Chemistry:	Alkynes (8)

522

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

108

Natural
Products

113

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101796

NSC-70220	Others	Cancer
NSC-70220 is a selective and allosteric SOS1 inhibitor. NSC-70220 inhibits allosteric site activation, and partially inhibited catalytic site activation. NSC-70220 has an anticancer effect .

HY-15827

NSC 405020 1 Publications Verification	MMP	Cardiovascular Disease Cancer
NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis .

HY-141687

NSC 107512	CDK Apoptosis	Cancer
NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors .

HY-134309

NSC 288387	Virus Protease	Infection
NSC 288387 is a pan-flavivirus MTase inhibitor. NSC 288387 binds to the SAM-binding pocket. NSC 288387 inhibits ZIKV with an IC₅₀ of 0.2 μM. NSC 288387 also inhibits viral replication in cell culture .

HY-152168

NSC 295642	PERK Phosphatase	Cancer
NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer .

HY-N0837

Veratramine

1 Publications Verification

NSC17821; NSC23880
Others Cancer

Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.

Veratramine 1 Publications Verification NSC17821; NSC23880	Others	Cancer
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.

HY-19539

NSC-658497	Ras	Cancer
NSC-658497 is an effective inhibitor of Ras-GEF, SOS1. NSC-658497 binds to SOS1, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity. NSC-658497 showed dose-dependent efficacy in inhibiting Ras, downstream signaling activities, and associated cell proliferation .

HY-118365

NSC 140873	Others	Infection Cancer
NSC 140873 is an inhibitor of the RUNX1-CBFβ interaction. NSC 140873 can be used for research of viral infection and leukemia. NSC 140873 has an unstable structure and can be converted spontaneously in solution to a benzodiazepine (Ro5-3335) .

HY-B1714

NSC 601980 analog	Others	Cancer
NSC 601980 analog is the analog of the NSC601980, NSC601980 shows antitumor activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.6 and -6.9 respectively.

HY-122258

NSC-370284	STAT TET Protein	Cancer
NSC-370284 is a selective inhibitor of ten-eleven translocation 1 (TET1) and 5-hydroxymethylcytosine (5hmC). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5 .

HY-110185

NSC 617145	DNA/RNA Synthesis	Cancer
NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor with an IC₅₀ value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks (DSB) and chromosomal abnormalities. NSC 617145 shows selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases .

HY-125169

NSC 185058

Autophagy Atg4 Cancer

NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity .
HY-B1476

NSC 42196

Endogenous Metabolite Metabolic Disease

NSC 42196 is an endogenous metabolite.
HY-18594

NSC-41589

Others Others

NSC-41589 is an N-[2-(methylsulfanyl) phenyl]acetamide.

NSC 185058	Autophagy Atg4	Cancer
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity .

NSC 42196	Endogenous Metabolite	Metabolic Disease
NSC 42196 is an endogenous metabolite.

NSC-41589	Others	Others
NSC-41589 is an N-[2-(methylsulfanyl) phenyl]acetamide.

HY-156780

NSC 689534 1 Publications Verification	Cuproptosis	Cancer
NSC 689534 can form copper chelate with Cu ²⁺. NSC 689534/Cu ²⁺ complex is a potent oxidative stress inducer, and has antitumor activity .

HY-147290

NSC 694623	Histone Acetyltransferase	Cancer
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC₅₀ value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF). NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer .

HY-145330

NSC639828	DNA/RNA Synthesis	Cancer
NSC639828 is a potent inhibitor of DNA polymerase α with an IC₅₀ of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease .

HY-156328

NSC 48160	Apoptosis	Cancer
NSC 48160 inhibits the growth of the pancreatic cancer cells with IC₅₀s of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. NSC 48160 also induces pancreatic cancer cell apoptosis. NSC 48160 can improve metabolic syndromes, such as NASH, obesity and lipid metabolism disorders .

HY-147288

NSC 694621	Histone Acetyltransferase	Cancer
NSC 694621 is a potent PCAF inhibitor, with an IC₅₀ of 5.71 µM (PCAF/H3_1-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells .

HY-147289

NSC 698600	Histone Acetyltransferase	Cancer
NSC 698600 is a potent PCAF inhibitor, with IC₅₀ of 6.51 µM (PCAF/H3_1-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells .

HY-144444

NSC381467	EGFR	Cancer
NSC381467 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC381467 has strong antiproliferative activities. NSC381467 has the potential for the research of cancer diseases .

HY-144445

NSC114126	EGFR	Cancer
NSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases .

HY-19387

Didox

5+ Cited Publications

NSC-324360
DNA/RNA Synthesis Cancer

Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.
HY-15723A

NSC 23766 trihydrochloride

25+ Cited Publications

Ras Apoptosis Cancer

NSC 23766 trihydrochloride is an inhibitor of Rac1 activation.

Didox 5+ Cited Publications NSC-324360	DNA/RNA Synthesis	Cancer
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.

NSC 23766 trihydrochloride 25+ Cited Publications	Ras Apoptosis	Cancer
NSC 23766 trihydrochloride is an inhibitor of Rac1 activation.

HY-137843

NSC 80467	DNA/RNA Synthesis	Cancer
NSC 80467, a DNA damaging agent, selectively inhibits survivin. NSC 80467 preferentially inhibits DNA synthesis and results in induction of γH2AX and pKAP1, two markers of DNA damage .

HY-103366

NSC 109555 ditosylate	Checkpoint Kinase (Chk)	Cancer
NSC 109555 ditosylate is a potent, selective, ATP-competitive checkpoint kinase 2 (Chk2) inhibitor with an IC₅₀ of 240 nM. NSC 109555 ditosylate can be used for the research of cancer .

HY-122066

NSC47924	Others	Infection
NSC47924 is a laminin receptor (LR) inhibitor. NSC47924 affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. NSC47924 can be used for testing prion diseases .

HY-106423

Mivobulin NSC 613862; (S)-(-)-NSC 613862	Microtubule/Tubulin	Cancer
Mivobulin (NSC 613862) is a tubulin inhibitor, binds to tubulin in the region that overlaps the colchicine site, and inhibits tubulin polymerization. Mivobulin (NSC 613862) promotes the formation of abnormal polymers and a GTPase activity in the tubulin dimer. Anti-cancer activity .

HY-17393

Carboplatin 40+ Cited Publications NSC 241240	DNA Alkylator/Crosslinker Autophagy DNA/RNA Synthesis	Cancer
Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.

HY-123510

NSC-670224

Others Others

NSC-670224 is toxic to Saccharomyces cerevisiae at low micromolar concentration (LC₅₀: 3.2 μM) .
HY-118851

NSC-77053

Others Others

NSC-77053 is a potent BoNT/E inhibitor with an IC₅₀ and a K_i of 2.4 μM and 1.29 μM, respectively .

NSC-670224	Others	Others
NSC-670224 is toxic to Saccharomyces cerevisiae at low micromolar concentration (LC₅₀: 3.2 μM) .

NSC-77053	Others	Others
NSC-77053 is a potent BoNT/E inhibitor with an IC₅₀ and a K_i of 2.4 μM and 1.29 μM, respectively .

HY-144105

NSC405640	MDM-2/p53	Cancer
NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53 .

HY-19820A

NSC45586 sodium	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 sodium is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 sodium targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons .

HY-19820

NSC45586	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons .

HY-108937

NSC 15364

5+ Cited Publications

VDAC Apoptosis Cardiovascular Disease Neurological Disease

NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis .

NSC 15364 5+ Cited Publications	VDAC Apoptosis	Cardiovascular Disease Neurological Disease
NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis .

HY-18756

NSC-87877	SHP2 Phosphatase Apoptosis	Others
NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC₅₀ values of 0.318 μM, 0.355 μM shp2 and shp1, respectively . NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26) .

HY-114658

Daunomycinone

NSC-109351
Biochemical Assay Reagents Cancer

Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity .
HY-144441

NSC81111

EGFR Cancer

NSC81111 is a potent and orally active EGFR-TK inhibitor with an IC₅₀ of 0.15 nM. NSC81111 has anticaner effects .
HY-15733

Lucidin

1 Publications Verification

NSC 30546
Others Cancer

Lucidin (NSC 30546) is a natural component of Rubia cordifolia.

Daunomycinone NSC-109351	Biochemical Assay Reagents	Cancer
Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity .

NSC81111	EGFR	Cancer
NSC81111 is a potent and orally active EGFR-TK inhibitor with an IC₅₀ of 0.15 nM. NSC81111 has anticaner effects .

Lucidin 1 Publications Verification NSC 30546	Others	Cancer
Lucidin (NSC 30546) is a natural component of Rubia cordifolia.

HY-115492

NSC668394 1 Publications Verification	PKC	Cancer
NSC668394 is a potent ezrin (Thr567) phosphorylation inhibitor, with a K_d of 12.59 μM. NSC668394 inhibit ezrin T567 phosphorylation caused by PKCΙ primarily via their binding to ezrin. NSC668394 can be used to prevent tumor metastasis .

HY-103380

NSC 625987 1 Publications Verification	CDK	Cancer
NSC 625987 is a specific and high-affinity CDK4 inhibitor with an IC₅₀ of 0.2 μM for CDK4:cyclin D1. NSC 625987 shows >500-fold selectivity for CDK4 over CDK2 .

HY-119172

NSC-60339	Bacterial	Infection Inflammation/Immunology Cancer
NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent .

HY-117666

NSC668036 1 Publications Verification	Wnt	Inflammation/Immunology
NSC668036 is a Dishevelled (Dvl) PDZ domain inhibitor with a K_d of 237 µM. NSC668036 blocks Wnt signaling by interrupting the Frizzled-Dvl interaction .

HY-108638

NSC 146109 hydrochloride 1 Publications Verification	MDM-2/p53 Apoptosis	Cancer
NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and can be used for breast cancer research. NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes .

HY-123786

NSC745887

Others Cancer

NSC745887 (compound 25) is an anti-cancer agent. NSC745887 exhibits dose-dependent inhibition of proliferation in all 60 cancer cell lines .

NSC745887	Others	Cancer
NSC745887 (compound 25) is an anti-cancer agent. NSC745887 exhibits dose-dependent inhibition of proliferation in all 60 cancer cell lines .

HY-111163

NSC49652	Apoptosis	Cancer
NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75 ^NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75 ^NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells .

HY-130369

NSC10010 hydrochloride	Bacterial Necroptosis HSV	Infection Cancer
NSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase .

HY-52155S

NSC 89275-d12

Isotope-Labeled Compounds Others

NSC 89275-d₁₂ is the deuterium labeled NSC 89275[1].
HY-Y0226S1

NSC 1940-d8

Isotope-Labeled Compounds Others

NSC 1940-d₈ is the deuterium labeled NSC 1940[1].
HY-Y0226S2

NSC 1940-d4

Isotope-Labeled Compounds Others

NSC 1940-d₄ is the deuterium labeled NSC 1940[1].

Cat. No.	Product Name	Target	Research Area

HY-W039756

Boc-Ala-Ala-OH

NSC 334362
Amino Acid Derivatives Others

Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .

HY-W010955

Z-Phe-Leu-OH NSC 334018	Biochemical Assay Reagents	Others
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .

HY-P4698

Tri-valine NSC 35938	Peptides	Metabolic Disease
Tri-valine (NSC 35938) is a polypeptide that can be separated from Creatine kinase (HY-P2799), β-enolase, Triosephosphate isomerase (HY-P2931) and glyceraldehyde 3-phosphate dehydrogenase .

HY-P4644

Tryptophylleucine NSC 286600	Peptides	Others
Tryptophylleucine (NSC 286600) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4647

Tryptophyltryptophan NSC 524592	Peptides	Others
Tryptophyltryptophan (NSC 524592) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4631

Tryptophylalanine NSC 97949	Peptides	Others
Tryptophylalanine (NSC 97949) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4663

Val-Gly-Ser-Glu NSC 350591	Peptides	Cancer
Val-Gly-Ser-Glu (NSC 350591) is an ECF-A tetrapeptide. Val-Gly-Ser-Glu dose-dependently increases the number of human eosinophils, but not neutrophils, rosetting with complement-coated sheep erythrocytes (EAC3b) .

HY-P5012

Cbz-Glu-Gly-OH NSC 186902	Peptides	Others
Cbz-Glu-Gly-OH (NSC 186902) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5024

Cbz-Ile-Pro-OH NSC 333754	Peptides	Others
Cbz-Ile-Pro-OH (NSC 333754) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4711

N-β-Alanyl-β-alanine NSC 97926	Peptides	Others
N-β-Alanyl-β-alanine (NSC 97926) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-15400

Boc-D-Thr(Bzl)-OH

NSC 337217; NSC337217; NSC-337217
Amino Acid Derivatives Others

Boc-D-Thr(Bzl)-OH is a threonine derivative .

HY-N6693

Valinomycin 3 Publications Verification NSC 122023	Apoptosis Antibiotic Autophagy Fungal	Infection Others Cancer
Valinomycin is a potassium-specific ionophore, the valinomycin-K ⁺ complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K ⁺ gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .

HY-B1732

DL-3-Phenylalanine

DLPA; NSC 9959
Amino Acid Derivatives Others

DL-3-Phenylalanine is a phenylalanine derivative .

HY-W141916

Pentaglycine Tetraglycylglycine; Gly-Gly-Gly-Gly-Gly; NSC 96353	Peptides	Infection
Pentaglycine (Tetraglycylglycine) is a bridge containing five glycine molecules. Pentaglycine can form highly cross-linked peptidoglycan. Glucose reduced expression of pentaglycine. Pentaglycine is cleaved by lysostaphin, and occurs in the cell envelope of staphylococci .

HY-Y0978

Boc-Glycine

N-tert-Butoxycarbonyl-2-aminoacetic acid; NSC 127669
Amino Acid Derivatives Others

Boc-Glycine is a Glycine (HY-Y0966) derivative .
HY-15580

Dolastatin 10

DLS 10; NSC 376128
Microtubule/Tubulin ADC Cytotoxin Cancer

Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization.
HY-41060

tert-Butoxycarbonyl-D-valine

N-tert-Butyloxycarbonyl-D-valine; NSC 334316
Amino Acid Derivatives Others

tert-Butoxycarbonyl-D-valine is a valine derivative .
HY-107848

DL-O-Tyrosine

NSC 72345; Ortho-tyrosine; o-DL-Tyrosine; o-Tyrosine
Amino Acid Derivatives Others

DL-O-Tyrosine is a tyrosine derivative .
HY-I0591

N-Formyl-L-leucine

N-Formyl-S-leucine; N-Formylleucine; NSC 334321
Amino Acid Derivatives Others

N-Formyl-L-leucine is a leucine derivative .

HY-79708A

O-Methyl-D-valine hydrochloride Methyl (R)-2-amino-3-methylbutanoate hydrochloride; Methyl D-valinate hydrochloride; NSC 22921	Amino Acid Derivatives	Others
O-Methyl-D-valine (hydrochloride) is a valine derivative .

HY-Y0555A

D-N-(Benzyloxycarbonyl)leucine N-(Benzyloxycarbonyl)-D-leucine; N-Carbobenzoxy-D-leucine; N-Carbobenzyloxy-D-leucine; NSC 523826	Amino Acid Derivatives	Others
D-N-(Benzyloxycarbonyl)leucine is a leucine derivative .

HY-Y1250

Fmoc-Gly-OH Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; N-Fluorenylmethoxycarbonylglycine; NPC 14692; NSC 334288; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid	Amino Acid Derivatives	Others
Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0837

Veratramine 1 Publications Verification NSC17821; NSC23880	Alkaloids Piperidine Alkaloids other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Others
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.

HY-B1476

NSC 42196	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
NSC 42196 is an endogenous metabolite.

HY-15733

Lucidin 1 Publications Verification NSC 30546	Quinones Classification of Application Fields Anthraquinones Source classification Rubiaceae Phenols Polyphenols Plants Disease Research Fields Cancer Rubia cordifolia L.	Others
Lucidin (NSC 30546) is a natural component of Rubia cordifolia.

HY-114557

NSC 90469 3,5-Diiodo-L-thyronine	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 90469 is an endogenous metabolite.

HY-15753

Ellipticine 3 Publications Verification NSC 71795	Apocynaceae Alkaloids Classification of Application Fields Source classification Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Indole Alkaloids Cancer	Topoisomerase
Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.

HY-15753A

Ellipticine hydrochloride 3 Publications Verification NSC 71795 hydrochloride	Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Indole Alkaloids Cancer	Topoisomerase
Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.

HY-N3738

Demethoxycentaureidin NSC 689466	Structural Classification Flavonoids Flavones Source classification Peucephyllum schottii A.Gray Plants Compositae	Others
Demethoxycentaureidin (NSC 689466) is a natural product that can be isolated from Peucephyllum schottii .

HY-79494

Glyoxalic acid 1 Publications Verification NSC 27785; Formylformic acid; Oxalaldehydic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glyoxalic acid (NSC 27785) is an organic compound that is both an aldehyde and a carboxylic acid.

HY-N4277

Methyl protogracillin NSC-698793	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Others
Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity .

HY-N1107

Uzarigenin NSC 119993; NSC 277290; Odorigeni	Apocynaceae Structural Classification Cardiacglycosides Source classification Plants Steroids	Others
Uzarigenin (NSC 119993; NSC 277290; Odorigeni) is a carnolide can be isolated from Pergularia tomentosa and exhibits antiproliferative activity. Uzarigenin resists the proliferation of PC3 cells, HeLa cells, Calu-1 cells, MCF-7 cells and U251MG cells, with IC₅₀ values of 0.3 μM, 3.0 μM, 8.0 μM, 6.0 μM and 6.0 μM respectively .

HY-19543

Brusatol 20+ Cited Publications NSC 172924	Structural Classification Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr. Cancer	Keap1-Nrf2 Apoptosis
Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent . Brusatol increases cellular apoptosis .

HY-N10687

Saprorthoquinone NSC 648341	Quinones Structural Classification Labiatae Source classification Plants Naphthalene Quinones Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	Others
Saprorthoquinone (NSC 648341) is a diterpenoid that can be found in salvia atropatana. Saprorthoquinone shows cytotoxicity for PC3 cells .

HY-114502

Chrysanthemic acid NSC 11779	Structural Classification Tanacetum cinerariifolium (Treviranus) Schultz Bipontinus Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others .

HY-Y0057

NSC 13138 Cinchoninic acid (6CI,7CI,8CI); 4-Carboxyquinoline	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 13138 is an endogenous metabolite.

HY-N4315

Pomiferin NSC 5113	Classification of Application Fields Source classification Phenols Polyphenols Maclura pomifera (Raf.) Schneid. Plants Moraceae Disease Research Fields Cancer	HDAC mTOR
Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC₅₀ of 1.05 μM, and also potently inhibits mTOR (IC₅₀, 6.2 µM).

HY-N1293

Serpentinine NSC72123	Apocynaceae Rauvolfia verticillata (Lour.) Baill. Structural Classification Alkaloids Rauvolfia serpentina Source classification Plants Indole Alkaloids	Others
Serpentinine (NSC72123) is an alkaloid isolated from Rauwolfia serpentina Benth .

HY-B1777

Spermine 3 Publications Verification NSC 268508; Neuridine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Influenza Virus
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.

HY-Y0124

NSC 16590 α,α-Dimethylglycine; α-Aminoisobutanoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Pterocarpus soyauxii Taub. Source classification Other Diseases Plants Compositae Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-114917

Aldophosphamide NSC 254	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research .

HY-13764

Tetrandrine 5+ Cited Publications NSC-77037; d-Tetrandrine	Stephania tetrandra S. Moore Alkaloids Structural Classification Classification of Application Fields Source classification Plants Menispermaceae Inflammation/Immunology Disease Research Fields Alkaloid Dimers	Calcium Channel Potassium Channel Parasite
Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca ²⁺ current (ICa) and Ca ²⁺-activated K ⁺ current.

HY-N0034

Arctiin 3 Publications Verification Arctii; NSC 315527; Arctigenin-4-glucoside	Structural Classification Natural Products Classification of Application Fields Anti-aging Source classification Lignans Phenylpropanoids Plants Compositae Caesalpinia magnifoliolata Metc. Disease Research Fields Cancer	NF-κB
Arctiin (NSC 315527) is a plant lignan extracted from burdock seeds and has anti-cancer activity.

HY-112058

Distamycin A NSC-82150	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Apoptosis
Distamycin A (NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis .

HY-Y1644

NSC 8751 (E)-2-Butenoic acid; (E)-Crotonic acid; trans-2-Butenoic acid; trans-Crotonic acid; trans-3-Methylacrylic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 8751 is an endogenous metabolite.

HY-N0004

Oridonin 15+ Cited Publications NSC-250682; Isodonol	Infection Structural Classification Classification of Application Fields Terpenoids Labiatae Diterpenoids Plants Emilia sonchifolia (L.) DC. Inflammation/Immunology Disease Research Fields	Akt Bacterial
Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC₅₀s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.

HY-Y0148

10-Hydroxydecanoic acid NSC 15139	Structural Classification Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Others
10-Hydroxydecanoic acid (NSC 15139) is a saturated fatty acid of 10-hydroxy-trans-2-decenoic acid from royal jelly, with anti-inflammatory activity .

HY-101413

Iberin 1 Publications Verification NSC 321801	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Cancer	Apoptosis Endogenous Metabolite Bacterial
Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC₅₀ of 2.3 μM in HL60 cell. Iberin induces apoptosis.

HY-114772

Methyl reserpate NSC 81464; Me reserpate	Apocynaceae Structural Classification Alkaloids Source classification Rauvolfia vomitoria Afzel. Plants	Others
Methyl reserpate (NSC 81464) is a Yohimbine (HY-12715) type alkaloid, that can be isolated from Rauwolfia vomitoria roots and leaves .

HY-105529

Indicine N-oxide (+)-Indicine N-oxide; NSC 132319	Alkaloids Structural Classification Pyrrole Alkaloids Classification of Application Fields Tournefortia argentea Linnaeus f. Source classification Plants Disease Research Fields Boraginaceae Cancer	Others
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .

HY-B0504

Creatinine 2 Publications Verification NSC13123	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease markers Metabolic Disease Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-105697

Protoveratrine A NSC 7526; Protalba; Protoveratrin	Structural Classification Alkaloids Piperidine Alkaloids Veratrum nigrum Linn. Liliaceae Source classification Plants	Others
Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases .

HY-13555

β-Lapachone 5+ Cited Publications ARQ-501; NSC-26326	Quinones Structural Classification other families Classification of Application Fields Source classification Plants Naphthalene Quinones Disease Research Fields Cancer	Topoisomerase Autophagy Apoptosis
β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.

HY-118166

Gentisein NSC 329491; 1,3,7-Trihydroxyxanthone	other families Xanthones Classification of Application Fields Neurological Disease Source classification Phenols Polyphenols Plants Disease Research Fields	5-HT Receptor
Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC₅₀ value of 4.7 µM .

HY-118384

Sangivamycin 2 Publications Verification NSC 65346; BA-90912	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	PKC Nucleoside Antimetabolite/Analog
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-N1393

2-Methoxybenzoic acid NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-N0841

Bruceine A 3 Publications Verification Dihydrobrusatol; NSC310616	Infection Triterpenes Simaroubaceae Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Brucea javanica (L.) Merr.	Parasite Antibiotic
Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.

HY-N3627

Coronalolide methyl este NSC 680073	Structural Classification Natural Products Source classification Rubiaceae Plants Gardenia jasminoides Ellis	Others
Coronalolide methyl ester (NSC 680073) is a natural triterpene with anticancer effects. Coronalolide methyl ester shows moderately cytotoxic to KATO-3, SW-620, and Hep-G2 cells., with IC₅₀ values of 8.64 µg/mL, 6.19 µg/mL, and 6.8 µg/mL, respectively .

HY-32736

Triptonide 2 Publications Verification NSC 165677; PG 492	Classification of Application Fields Terpenoids Source classification Celastraceae Diterpenoids Plants Tripterygium wilfordii Hook. f. Disease Research Fields Inflammation/Immunology	Wnt β-catenin Apoptosis Autophagy
Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC₅₀ of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .

HY-N0863

Methyl protodioscin NSC-698790; Smilax saponin B	other families Classification of Application Fields Source classification Plants Disease Research Fields Steroids Cancer	Apoptosis
Methyl protodioscin(NSC-698790) is a furostanol bisglycoside with antitumor properties; shows to reduce proliferation, cause cell cycle arrest.

HY-B0751

Fumagillin Amebacilin; NSC9168	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite HIV Antibiotic
Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-17470

Mizoribine 4 Publications Verification NSC 289637; HE 69	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	HCV SARS-CoV Antibiotic Parasite
Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC₅₀ of approximately 100 μM for anti-HCV activity. Immunosuppressant . Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC₅₀s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively .

HY-N0840

Bruceantin 1 Publications Verification (-)-Bruceantin; NCI165563; NSC165563	Simaroubaceae Classification of Application Fields Brucea antidysenterica J.F.Mill. Terpenoids Source classification Diterpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	Others
Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.

HY-134000

Emodic acid NSC624610	Quinones Structural Classification Human Gut Microbiota Metabolites Microorganisms Leguminosae Cercis chinensis Bunge Anthraquinones Source classification Plants Endogenous metabolite	p38 MAPK NF-κB ERK JNK VEGFR MMP
Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells .

HY-N0142

Phloretin 10+ Cited Publications NSC 407292; RJC 02792	Structural Classification Classification of Application Fields Source classification Rosaceae Plants Dihydrochalcones Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Malus pumila Mill. Phenols Polyphenols Disease Research Fields Cancer	SGLT Endogenous Metabolite GLUT
Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC₅₀values of 49 μM and 61 μM, respectively .Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation .

HY-N0142R

Phloretin (Standard) NSC 407292 (Standard); RJC 02792 (Standard)	Structural Classification Human Gut Microbiota Metabolites Flavonoids Classification of Application Fields Source classification Malus pumila Mill. Rosaceae Phenols Plants Endogenous metabolite Disease Research Fields Cancer	SGLT Endogenous Metabolite GLUT
Phloretin (Standard) is the analytical standard of Phloretin. This product is intended for research and analytical applications. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC₅₀values of 49 μM and 61 μM, respectively .Phloretin has the potential for the treatment of rheumatoid arthritis (RA)?and allergic airway inflammation .

HY-107850

Pregnanediol NSC 1612; NSC 47462	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo .

HY-18980

Rottlerin 5+ Cited Publications Mallotoxin; NSC 56346; NSC 94525	Structural Classification Chalcones Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Euphorbiaceae Plants Disease Research Fields Mallotus philippensis Cancer	PKC Autophagy Apoptosis HIV RABV
Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC₅₀ values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation . Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection .

HY-N0003

Honokiol Maximum Cited Publications 42 Publications Verification NSC 293100	Structural Classification Magnolia officinalis. Rehd. et Wils. Classification of Application Fields Source classification Magnoliaceae Lignans Phenylpropanoids Plants Disease Research Fields Cancer	Akt Autophagy HCV ERK
Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier .

HY-N6693

Valinomycin 3 Publications Verification NSC 122023	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Apoptosis Antibiotic Autophagy Fungal
Valinomycin is a potassium-specific ionophore, the valinomycin-K ⁺ complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K ⁺ gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .

HY-N6746

Citrinin NSC 186	Infection Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Bacterial Fungal Endogenous Metabolite
Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess a broad spectrum of bioactivities, including antibacterial, antifungal, and potential anticancer and neuro-protective effects in vitro .

HY-13674

Maytansine NSC 153858	Alkaloids Source classification Celastraceae Plants Maytenus hookeri Loes. Disease Research Fields Cancer	Microtubule/Tubulin
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations .

Cat. No.	Product Name	Chemical Structure

HY-52155S

NSC 89275-d12

NSC 89275-d₁₂ is the deuterium labeled NSC 89275[1].
HY-Y0226S1

NSC 1940-d8

NSC 1940-d₈ is the deuterium labeled NSC 1940[1].
HY-Y0226S2

NSC 1940-d4

NSC 1940-d₄ is the deuterium labeled NSC 1940[1].
HY-Y0085S

NSC 190686-d3

NSC 190686-d₃ is the deuterium labeled NSC 190686[1].
HY-Y1675S

NSC 65593-d4

NSC 65593-d₄ is the deuterium labeled NSC 65593[1].

HY-17393S

Carboplatin-d4
Carboplatin-d₄ is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.

HY-Y0124S

NSC 16590-d6

NSC 16590-d₆ is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.
HY-79576S

NSC 88911-d3

NSC 88911-d₃ is the deuterium labeled NSC 88911[1].
HY-79576S2

NSC 88911-13C6

NSC 88911- ¹³C₆ is a ¹³C-labeled 3-(4-Chlorophenyl)-1-methoxy-1-methylurea[1].
HY-Y1630S

NSC 10281-d4

NSC 10281-d₄ is the deuterium labeled NSC 10281[1].
HY-Y0093S

NSC 5416-d14

NSC 5416-d₁₄ is the deuterium labeled NSC 5416[1].
HY-Y1644S

NSC 8751-d6

NSC 8751-d₆ is the deuterium labeled NSC 8751[1]. NSC 8751 is an endogenous metabolite[2].

HY-B0504S2

Creatinine-d5
Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-123533S

Resorufin-d6

Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

HY-B0504S1

Creatinine-13C
Creatinine- ¹³C is the ¹³C-labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-W016389S

9H-Fluoren-2-ol-d9

9H-Fluoren-2-ol-d₉ (NSC 31248-d₉) is a deuterium labeled compound.
HY-B0246S3

Carbamazepine-(Ph)d8

Carbamazepine-(Ph)d8 (CBZ-(Ph)d8; NSC 169864-(Ph)d8) is the deuterium labeled Carbamazepine-(Ph) (HY-B0246) .

HY-N5034S

Phosphorylethanolamine-d4
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-14655S1

Sulfasalazine-d3,15N
Sulfasalazine-d₃, ¹⁵N is ¹⁵N and deuterated labeled Sulfasalazine (HY-14655). Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer .

HY-N1150S10

Thymidine-d14
Thymidine-d₁₄ (DThyd-d₁₄; NSC 21548-d₁₄) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-N6746S1

Citrinin-13C13

Citrinin- ¹³C₁₃ (NSC 186- ¹³C₁₃) is the ¹³C labeled Citrinin (HY-N6746) . Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess a broad spectrum of bioactivities, including antibacterial, antifungal, and potential anticancer and neuro-protective effects in vitro .

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-Y0219S1

1,2,4-Triazole-d3

NSC 83128-d₃ is the deuterium labeled NSC 83128[1].
HY-Y0251S

3-Nitrophthalic acid-d3

NSC 3120-d₃ is the deuterium labeled NSC 3120[1].

HY-N1150S11

Thymidine-13C10
Thymidine- ¹³C₁₀ (DThyd- ¹³C₁₀; NSC 21548- ¹³C₁₀) is ¹³C-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-Y0219S

1,2,4-Triazole-13C2,15N3

NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-N1393S

2-Methoxybenzoic acid-13C6
2-Methoxybenzoic acid- ¹³C₆ is the ¹³C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-B0678S

Metaxalone-d3

Metaxalone-d₃ is the deuterium labeled Metaxalone. Metaxalone (AHR438;NSC170959) is a muscle relaxant used to relax muscles.
HY-B0139S

Flucytosine-13C,15N2

Flucytosine- ¹³C, ¹⁵N₂ (NSC 103805- ¹³C, ¹⁵N₂; Ro 2-9915- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled Flucytosine (HY-B0139).
HY-W017475S

4-Nitrobenzonitrile-d4

4-Nitrobenzonitrile-d₄ is the deuterium labeled NSC 88911[1].

HY-107850S

Pregnanediol-d5
Pregnanediol-d₅ is the deuterium labeled Pregnanediol. Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo[1].

HY-14655S

Sulfasalazine-d4
Sulfasalazine-d₄ is the deuterium labeled Sulfasalazine. Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer[1][2][3][4].

HY-B0504S

Creatinine-d3

Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].
HY-B1556S

Benzyl salicylate-d4

Benzyl salicylate-d₄ is the deuterium labeled Benzyl salicylate[1].

HY-34439S1

2,5-Dimethylpyrazine-d3
2,5-Dimethylpyrazine-d₃ is deuterated labeled γ-Terpinene (HY-W020183). γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity .

HY-Y0957S

2,5-Difluorobenzoic acid-d3

2,5-Difluorobenzoic acid-d₃ is the deuterium labeled 2,5-Difluorobenzoic acid[1].

HY-17364S

Temozolomide-d3

Temozolomide-d₃ is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].

HY-B0217S

Nitazoxanide-d4

Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-N1150S1

Thymidine-d4
Thymidine-d₄ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

HY-B0246S

Carbamazepine-d10

Carbamazepine-d₁₀ is the deuterium labeled Carbamazepine. Carbamazepine (CBZ), a sodium channel blocker, is an anticonvulsant agent[1][2].

HY-N1150S

Thymidine-d3
Thymidine-d₃ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

HY-B0246S1

Carbamazepine-d2

Carbamazepine-d₂ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.

HY-13502S

Mitoxantrone-d8
Mitoxantrone-d₈ (mitozantrone-d8) is the deuterium labeled Mitoxantrone. Mitoxantrone is a topoisomerase II inhibitor and also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM[1][2].

HY-B0094S

Artemisinin-d3

Artemisinin-d₃ is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].

HY-N1150S2

Thymidine-13C
Thymidine- ¹³C is the ¹³C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]

HY-N1150S6

Thymidine-d2
Thymidine-d₂ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1

HY-B0246S2

Carbamazepine-d8

Carbamazepine-d₈ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent, with an IC50 of 131 μM[1][2].

HY-15345AS

Tetrahydrouridine-d3
Tetrahydrouridine-d₃ is the deuterium labeled Tetrahydrouridine[1]. Tetrahydrouridine dihydrate is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine[2][3].

HY-N0054S

Osthole-d3

Osthole-d₃ (Osthol-d₃) is the deuterium-labeled Osthole (HY-N0054) .

HY-13502AS

Mitoxantrone-d8 dihydrochloride

Mitoxantrone-d₈ dihydrochloride is deuterated labeled Mitoxantrone dihydrochloride (HY-13502A). Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity . Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

Cat. No.	Product Name		Classification

HY-12008

Erlotinib Hydrochloride Maximum Cited Publications 75 Publications Verification CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride		Alkynes
Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC₅₀ of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896

Erlotinib Maximum Cited Publications 75 Publications Verification CP-358774; NSC 718781; OSI-774		Alkynes
Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC₅₀ of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC₅₀ of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer . Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-12008S

Erlotinib-d6 hydrochloride CP-358774-d₆ hydrochloride; NSC 718781-d₆ hydrochloride; OSI-774-d₆ hydrochloride		Alkynes
Erlotinib-d₆ (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-12008A

Erlotinib mesylate CP-358774 mesylate; NSC 718781 mesylate; OSI-774 mesylate		Alkynes
Erlotinib mesylate (CP-358774 mesylate) inhibits purified EGFR kinase with an IC₅₀ of 2 nM. Erlotinib (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1341

Norethynodrel Enidrel; SC 4642; NSC 15432		Alkynes
Norethynodrel (Enidre) is a 19-nortestosterone derivative to be used as a progestagen. Norethynodrel can be used for researching inhibition of ovulation . Norethynodrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896S

Erlotinib-d6 CP-358774-d₆; NSC 718781-d₆; OSI-774-d₆		Alkynes
Erlotinib-d₆ (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896S1

Erlotinib-13C6 CP-358774-¹³C₆; NSC 718781-¹³C₆; OSI-774-¹³C₆		Alkynes
Erlotinib- ¹³C₆ is a ¹³C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

HY-12008S1

Erlotinib-13C6 hydrochloride CP-358774-¹³C₆ hydrochloride; NSC 718781-¹³C₆ hydrochloride; OSI-774-¹³C₆ hydrochloride		Alkynes
Erlotinib- ¹³C₆ (hydrochloride) is the ¹³C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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